![]() Left untreated, HIV reduces the number of CD4 cells in the body, making it more difficult for the immune system to fight off infections and other diseases. HIV: A virus that is transmitted through certain body fluids and weakens the immune system by destroying cells that fight disease and infection, specifically CD4 cells (often called T cells). ![]() 1 Today, there are approximately 39 million people currently living with HIV, and tens of millions of people have died of AIDS-related causes since the beginning of the epidemic. Approximately 86 million people have become infected with HIV since the start of the epidemic. HIV, the virus that causes AIDS (see box), has become one of the world’s most serious health and development challenges since the first cases were reported in 1981. government (U.S.), through PEPFAR (the President’s Emergency Plan for AIDS Relief), is the single largest donor to international HIV efforts in the world, including the largest donor to the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund). The focus now is on reaching the “95-95-95” targets by 2025. However, while gains have been made, they have been uneven, and the interim “90-90-90” targets were missed in 2020. Under Sustainable Development Goal 3, the global community agreed to aim to end the AIDS epidemic by 2030.In recent decades, major global efforts have been mounted to address the epidemic, and despite challenges, significant progress has been made in addressing HIV.Many people living with HIV or at risk for HIV infection do not have access to prevention, treatment, and care, and there is still no cure. ![]() Approximately 39 million people are currently living with HIV, and tens of millions of people have died of AIDS-related causes since the beginning of the epidemic.
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